Lesser-Known Causes of Peripheral Neuropathy

Peripheral neuropathy is commonly linked to diabetes, but there are many other lesser-known causes that may lead to nerve damage in your limbs. If you’re experiencing symptoms like tingling, burning, numbness, or weakness in your hands or feet, it’s worth exploring what might be behind your discomfort.

At Spinal Diagnostics, we specialize in identifying and treating the root causes of nerve pain, even when the source isn’t immediately obvious.

Non-diabetic causes of peripheral neuropathy

While diabetes is the most common cause, other factors can also damage peripheral nerves, including:

Autoimmune diseases — Conditions like lupus or rheumatoid arthritis can cause the immune system to attack nerves.
Infections — Viral infections such as shingles, HIV, or Lyme disease can affect nerve function.
Vitamin deficiencies — Especially B1, B6, B12, and E. A lack of these nutrients can impair nerve health.
Alcoholism — Chronic alcohol abuse leads to poor nutrition and nerve damage over time.
Medications — Certain chemotherapy drugs, antibiotics, or antivirals can be toxic to nerves.
Inherited disorders — Genetic conditions like Charcot-Marie-Tooth disease can affect the peripheral nerves.

Recognizing the symptoms

Symptoms of peripheral neuropathy can vary depending on which nerves are affected, but common signs include:

Sharp, burning, or stabbing pain
Tingling or “pins and needles” sensations
Loss of coordination or balance
Muscle weakness
Heightened sensitivity to touch

Symptoms may begin gradually and worsen over time. It’s important to seek help early for the best chance at relief.

Take the First Step Toward Relief

From spine injections to nerve blocks and cutting-edge therapies, we help you move forward, pain free.

Schedule an appointment

Diagnosis and treatment options

At Spinal Diagnostics, we start with a thorough evaluation to determine what’s causing your nerve pain. We may use:

Electrodiagnostic testing (EMG/NCV)
Blood tests to identify deficiencies or autoimmune issues
Imaging tests to rule out structural causes

Once we identify the cause, we tailor a treatment plan that may include:

Medications to relieve nerve pain
Vitamin supplements if deficiencies are found
Physical therapy to improve strength and function
Nerve blocks or spinal cord stimulation for persistent pain

If you’ve been living with unexplained nerve symptoms, don’t assume it’s something you have to accept. Contact us today to schedule an appointment and get the answers you need.

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