Lesser-Known Causes of Peripheral Neuropathy

Peripheral neuropathy is commonly linked to diabetes, but there are many other lesser-known causes that may lead to nerve damage in your limbs. If you’re experiencing symptoms like tingling, burning, numbness, or weakness in your hands or feet, it’s worth exploring what might be behind your discomfort.
At Spinal Diagnostics, we specialize in identifying and treating the root causes of nerve pain, even when the source isn’t immediately obvious.
Non-diabetic causes of peripheral neuropathy
While diabetes is the most common cause, other factors can also damage peripheral nerves, including:
- Autoimmune diseases — Conditions like lupus or rheumatoid arthritis can cause the immune system to attack nerves.
- Infections — Viral infections such as shingles, HIV, or Lyme disease can affect nerve function.
- Vitamin deficiencies — Especially B1, B6, B12, and E. A lack of these nutrients can impair nerve health.
- Alcoholism — Chronic alcohol abuse leads to poor nutrition and nerve damage over time.
- Medications — Certain chemotherapy drugs, antibiotics, or antivirals can be toxic to nerves.
- Inherited disorders — Genetic conditions like Charcot-Marie-Tooth disease can affect the peripheral nerves.
Recognizing the symptoms
Symptoms of peripheral neuropathy can vary depending on which nerves are affected, but common signs include:
- Sharp, burning, or stabbing pain
- Tingling or “pins and needles” sensations
- Loss of coordination or balance
- Muscle weakness
- Heightened sensitivity to touch
Symptoms may begin gradually and worsen over time. It’s important to seek help early for the best chance at relief.
Diagnosis and treatment options
At Spinal Diagnostics, we start with a thorough evaluation to determine what’s causing your nerve pain. We may use:
- Electrodiagnostic testing (EMG/NCV)
- Blood tests to identify deficiencies or autoimmune issues
- Imaging tests to rule out structural causes
Once we identify the cause, we tailor a treatment plan that may include:
- Medications to relieve nerve pain
- Vitamin supplements if deficiencies are found
- Physical therapy to improve strength and function
- Nerve blocks or spinal cord stimulation for persistent pain
If you’ve been living with unexplained nerve symptoms, don’t assume it’s something you have to accept. Contact us today to schedule an appointment and get the answers you need.